NanoFrontier Liquid Chromatograph Mass Spectrometer ~NanoLC/Linear-Trap-TOF~

NanoFrontier -- Integrated NanoLC and Linear - Trap - TOF system. Innovative technology dedicated for the analysis of proteins. The highly efficient NanoFrontier is designed to meet the demanding challenges of today's proteomics research laboratories. The hybrid mass spectrometer incorporates Linear Ion Trap technology with TOF detection (Linear-Trap-TOF) affording superior sensitivity and mass accuracy.

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Features

NanoFrontier -- Unparalleled NanoLC performance and advanced Linear -Trap -TOF technology: Two Advanced Technologies MS:Linear-Trap-TOF NanoLC The Hitachi DEGS (Dual Exchange Gradient System, patent pending) technology provides accurate, true split-less nanoflow gradient formation (50nL/min). The NanoLC, with unparalleled split-less solvent delivery, is exclusive to Hitachi. The NanoLC consists of a dedicated gradient formation pump and a high precision nanoflow pump for stable solvent delivery. New Software  BA (Information Based Acquisition) affords efficient MS/MS performance for increased protein information and reduced analysis time. Example: The intelligent MS/MS analysis by internal database registration in real-time. For repetitive analyses, it is possible to record the retention time, mass number, and MS/MS data in the internal database in real-time. In subsequent runs of the same sample, MS/MS is performed on different parent ions, which minimizes overlapping MS/MS analyses. This enhanced MS/MS efficiency allows for increased protein information of low abundance ions. Additionally, the IBA process is applicable for comparisons between samples. Linear Ion Trap MSn Trap MSn analysis using the LIT enables automatic MS/MS with automatic peak selection and exclusion of monovalent ions. This is useful for detecting post-translation modifications such as phosphorylation and glycosylation sites. Application for Glycopeptides MSn analysis performed on ovalbumin using CID optimization. Dynamic Range The Hitachi-developed ADC（Analog to Digital Converter） offers a wide dynamic range, enabling quantitative applications in proteomics, biomarker identification, and metabolomics, as well as ensuring higher reliability of data.